How Do You Know When Your Thyroid Is Not Working
This article is part of a special study on Thyroid Disorders. To run across the other articles in this series, click hither.
In the concluding mail I explained that, for the vast majority of patients, hypothyroidism is an autoimmune disease. This isn't just an bookish distinction. Information technology's the reason both conventional and alternative treatments are so often ineffective.
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In this mail service I'm going to show you why taking replacement thyroid hormones without addressing the underlying immune imbalance is doomed to fail.
The ultimate result of hypothyroidism, whether it's caused past iodine deficiency or autoimmunity, is to decrease the amount of thyroid hormone available to the body. The conventional arroyo is to simply supplant these hormones with either constructed or bio-identical forms.
On the surface it seems like a reasonable approach. Patient doesn't accept enough hormones? Give more hormones. Uncomplicated, right?
Not and so much.
One time over again the conventional approach falls brusque because it ignores the underlying cause of the trouble. It'southward like taking Advil when you've got a pebble stuck in your shoe. It might work for a niggling while, and might even be necessary to dull the hurting. But you lot'd be a lot improve off if you took the pebble out of your shoe. Right?
Let'southward take a closer wait at why thyroid hormones oftentimes don't work, or end working over time. The following diagram illustrates how autoimmunity affects thyroid metabolism (delight notation, "HPT" stands for "hypothalamus-pituitary-thyroid centrality"):
Allowed dysregulation is some other term for autoimmune affliction. We nevertheless don't know exactly what causes information technology, but most researchers agree it's a mixture of genetic susceptibility and ecology factors such as iodine (excess), infection, pregnancy, nutrition and intestinal permeability.
In autoimmune disease the body attacks itself. It does this the same fashion it attacks strange invaders like bacteria and viruses: with T-cells, B-cells, natural killer cells, and cytotoxic T cells. The allowed response likewise involves proteins called cytokines, chemical messengers that pass letters between cells.
This self-attack past the immune system increases inflammation. And inflammation has a profound result on all aspects of thyroid metabolism and physiology.
First, inflammation suppresses the HPT axis. (1) One study showed a single injection of the inflammatory cytokine TNF-blastoff reduced claret levels of TSH, T3, gratis T4, free T3 and TRH for five days. (ii) This shows inflammation disrupts the product and regulatory mechanisms of thyroid hormones. Thyroid medication will increase the levels of T4 (and possibly T3), but it doesn't accost the other effects of HPT axis suppression.
Second, inflammation decreases both the number and sensitivity of thyroid hormone receptors. (3) If in that location aren't enough receptors, or they aren't sensitive plenty, it doesn't matter how much thyroid medication we have. The cells won't exist able to use it. It'south similar when my granddaddy used to decline his hearing aids while he was watching the football game. Information technology didn't matter how much my grandma yelled at him – he couldn't hear a word she said.
Third, inflammation decreases the conversion of T4 to T3. (four) T4 is the inactive form of thyroid hormone. The body has to convert information technology to the active T3 grade before it can be used. Most constructed hormone medications on the market are T4. If you give a T4 medication (like Synthroid, Levoxyl, Unithroid, etc.) to someone with inflammation, it's not going to piece of work because they tin can't convert the T4 to T3.
Patients who don't convert T4 to T3 well practice ameliorate on bio-identical hormones like Armour, because it contains both T4 and T3 (in a 4.22:1 ratio).
Inflammation disrupts thyroid metabolism in several other ways, but I recollect these 3 examples brand the point.
At present allow'due south review.
Inflammation causes HPT axis disruption, decreased receptor role, and decreased conversion of T4 to T3. Thyroid medication simply increases the levels of thyroid hormone (usually T4) in the blood. No thing how much we take, it's not going to restore HPT axis coordination, ameliorate receptor function, or increase conversion of T4 to T3.
The only way to practise that is to address the problem at its root past regulating the immune system and decreasing inflammation. (For more on how to address underlying inflammation, bank check out this episode of Revolution Wellness Radio with Izabella Wentz.) Unfortunately, this is rarely washed in either conventional or culling treatment of thyroid disorders.
Before I sign off, I merely desire to brand one thing clear. I'm not saying thyroid medication isn't necessary or useful. In fact, I recall it's an important part of treating Hashimoto's—especially when TSH is consistently elevated and T4 and T3 are consistently low. My point is thyroid medication is only 1 slice of the puzzle, and information technology won't be constructive on its ain unless the autoimmunity and inflammation are addressed.
If thyroid medication is the fantasy magic bullet of conventional medicine, iodine is the equivalent in alternative medicine. In the next post I'thousand going to explain why supplemental iodine may cause more than harm than good in Hashimoto's patients.
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<div form='gf_browser_chrome gform_wrapper qc_box_container_wrapper gform_legacy_markup_wrapper' id='gform_wrapper_9' ><form method='mail service' enctype='multipart/form-data' id='gform_9' grade='qc_box_container gform_legacy_markup' action='/three-reasons-why-your-thyroid-medication-isnt-working/' novalidate> <div form='gform_body gform-body'><ul id='gform_fields_9' class='gform_fields top_label form_sublabel_below description_below'><li id="field_9_1" class="gfield field gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible" ><label class='gfield_label' for='input_9_1' >Email<span course="gfield_required"><bridge class="gfield_required gfield_required_asterisk">*</span></span></label><div class='ginput_container ginput_container_email'> <input name='input_1' id='input_9_1' type='email' value='' class='large' placeholder='Your Email' aria-required="true" aria-invalid="imitation" /> </div></li><li id="field_9_2" grade="gfield health-business organisation field field_sublabel_below field_description_below gfield_visibility_visible" ><label class='gfield_label' for='input_9_2' >I desire to ameliorate my...</label><div class='ginput_container ginput_container_select'><select name='input_2' id='input_9_2' class='large gfield_select' aria-invalid="imitation" ><option value='' selected='selected' grade='gf_placeholder'>I desire to improve my...</choice><option value='Weight' >Weight</option><selection value='Free energy' >Energy</choice><option value='Digestion' >Digestion</choice><option value='Brain' >Brain</option><option value='Overall Wellness' >Overall Wellness</option><option value='All of the Above' >All of the Above</option></select></div></li><li id="field_9_4" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input proper noun='input_4' id='input_9_4' blazon='subconscious' course='gform_hidden' aria-invalid="fake" value='791' /></div></li><li id="field_9_5" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input proper noun='input_5' id='input_9_5' type='hidden' form='gform_hidden' aria-invalid="false" value='Heartburn/GERD' /></div></li></ul></div> <div grade='gform_footer top_label'> <input type='submit' id='gform_submit_button_9' class='gform_button button' value='Download eBook' onclick='if(window["gf_submitting_9"]){render imitation;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} ' onkeypress='if( event.keyCode == 13 ){ if(window["gf_submitting_9"]){return false;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} jQuery("#gform_9").trigger("submit",[true]); }' /> <input type='hidden' class='gform_hidden' name='is_submit_9' value='i' /> <input type='subconscious' form='gform_hidden' name='gform_submit' value='9' /> <input type='hidden' form='gform_hidden' name='gform_unique_id' value='' /> <input type='hidden' class='gform_hidden' name='state_9' value='WyJbXSIsIjVkYTAyNjYxOTg4ZDNhZGQwOTU0Yzc4NDcyNDk5YmM4Il0=' /> <input type='hidden' grade='gform_hidden' name='gform_target_page_number_9' id='gform_target_page_number_9' value='0' /> <input type='hidden' class='gform_hidden' proper name='gform_source_page_number_9' id='gform_source_page_number_9' value='i' /> <input type='subconscious' proper name='gform_field_values' value='popup_name=Heartburn%2FGERD' /> </div> <p mode="display: none !important;"><label>Δ<textarea proper name="ak_hp_textarea" cols="45" rows="viii" maxlength="100"></textarea></label><input type="hidden" id="ak_js_5" name="ak_js" value="93"/><script>document.getElementById( "ak_js_5" ).setAttribute( "value", ( new Date() ).getTime() );</script></p></course> </div>
[gravityform id="9" championship="false" description="false" field_values='popup_name=Gut Health']
<div grade='gf_browser_chrome gform_wrapper qc_box_container_wrapper gform_legacy_markup_wrapper' id='gform_wrapper_9' ><form method='mail' enctype='multipart/form-data' id='gform_9' class='qc_box_container gform_legacy_markup' activeness='/iii-reasons-why-your-thyroid-medication-isnt-working/' novalidate> <div course='gform_body gform-body'><ul id='gform_fields_9' class='gform_fields top_label form_sublabel_below description_below'><li id="field_9_1" class="gfield field gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible" ><label grade='gfield_label' for='input_9_1' >Electronic mail<bridge class="gfield_required"><span class="gfield_required gfield_required_asterisk">*</span></bridge></characterization><div class='ginput_container ginput_container_email'> <input proper noun='input_1' id='input_9_1' type='electronic mail' value='' class='big' placeholder='Your Email' aria-required="true" aria-invalid="false" /> </div></li><li id="field_9_2" class="gfield health-business organization field field_sublabel_below field_description_below gfield_visibility_visible" ><label class='gfield_label' for='input_9_2' >I desire to improve my...</label><div class='ginput_container ginput_container_select'><select name='input_2' id='input_9_2' class='large gfield_select' aria-invalid="false" ><option value='' selected='selected' course='gf_placeholder'>I want to meliorate my...</pick><pick value='Weight' >Weight</option><option value='Energy' >Energy</pick><option value='Digestion' >Digestion</option><option value='Brain' >Brain</option><option value='Overall Health' >Overall Health</option><option value='All of the Higher up' >All of the Above</option></select></div></li><li id="field_9_4" course="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div course='ginput_container ginput_container_text'><input name='input_4' id='input_9_4' type='subconscious' class='gform_hidden' aria-invalid="false" value='791' /></div></li><li id="field_9_5" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input name='input_5' id='input_9_5' type='hidden' class='gform_hidden' aria-invalid="false" value='Gut Health' /></div></li></ul></div> <div grade='gform_footer top_label'> <input type='submit' id='gform_submit_button_9' class='gform_button push' value='Download eBook' onclick='if(window["gf_submitting_9"]){return simulated;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} ' onkeypress='if( event.keyCode == 13 ){ if(window["gf_submitting_9"]){return fake;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} jQuery("#gform_9").trigger("submit",[true]); }' /> <input blazon='hidden' form='gform_hidden' name='is_submit_9' value='1' /> <input type='subconscious' class='gform_hidden' name='gform_submit' value='9' /> <input blazon='subconscious' class='gform_hidden' proper name='gform_unique_id' value='' /> <input blazon='hidden' class='gform_hidden' proper name='state_9' value='WyJbXSIsIjVkYTAyNjYxOTg4ZDNhZGQwOTU0Yzc4NDcyNDk5YmM4Il0=' /> <input type='hidden' class='gform_hidden' name='gform_target_page_number_9' id='gform_target_page_number_9' value='0' /> <input type='hidden' class='gform_hidden' name='gform_source_page_number_9' id='gform_source_page_number_9' value='ane' /> <input type='hidden' name='gform_field_values' value='popup_name=Gut+Health' /> </div> <p style="display: none !important;"><label>Δ<textarea name="ak_hp_textarea" cols="45" rows="8" maxlength="100"></textarea></label><input blazon="subconscious" id="ak_js_6" name="ak_js" value="189"/><script>document.getElementById( "ak_js_6" ).setAttribute( "value", ( new Appointment() ).getTime() );</script></p></form> </div>
[gravityform id="ix" title="false" description="imitation" field_values='popup_name=Food Additives']
<div course='gf_browser_chrome gform_wrapper qc_box_container_wrapper gform_legacy_markup_wrapper' id='gform_wrapper_9' ><course method='post' enctype='multipart/form-data' id='gform_9' grade='qc_box_container gform_legacy_markup' activeness='/three-reasons-why-your-thyroid-medication-isnt-working/' novalidate> <div class='gform_body gform-body'><ul id='gform_fields_9' class='gform_fields top_label form_sublabel_below description_below'><li id="field_9_1" course="gfield field gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible" ><label course='gfield_label' for='input_9_1' >Email<span form="gfield_required"><bridge form="gfield_required gfield_required_asterisk">*</span></span></label><div class='ginput_container ginput_container_email'> <input name='input_1' id='input_9_1' blazon='e-mail' value='' class='large' placeholder='Your Email' aria-required="true" aria-invalid="fake" /> </div></li><li id="field_9_2" class="gfield wellness-business organization field field_sublabel_below field_description_below gfield_visibility_visible" ><label class='gfield_label' for='input_9_2' >I desire to improve my...</characterization><div class='ginput_container ginput_container_select'><select name='input_2' id='input_9_2' class='large gfield_select' aria-invalid="fake" ><option value='' selected='selected' class='gf_placeholder'>I want to better my...</choice><selection value='Weight' >Weight</choice><option value='Energy' >Free energy</option><selection value='Digestion' >Digestion</option><pick value='Brain' >Brain</pick><choice value='Overall Health' >Overall Health</option><option value='All of the In a higher place' >All of the Above</option></select></div></li><li id="field_9_4" course="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div grade='ginput_container ginput_container_text'><input proper name='input_4' id='input_9_4' type='hidden' class='gform_hidden' aria-invalid="simulated" value='791' /></div></li><li id="field_9_5" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input name='input_5' id='input_9_5' blazon='hidden' form='gform_hidden' aria-invalid="false" value='Food Additives' /></div></li></ul></div> <div class='gform_footer top_label'> <input type='submit' id='gform_submit_button_9' class='gform_button button' value='Download eBook' onclick='if(window["gf_submitting_9"]){return faux;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} ' onkeypress='if( event.keyCode == 13 ){ if(window["gf_submitting_9"]){render fake;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=truthful;} jQuery("#gform_9").trigger("submit",[true]); }' /> <input type='hidden' class='gform_hidden' proper name='is_submit_9' value='1' /> <input blazon='hidden' class='gform_hidden' name='gform_submit' value='ix' /> <input type='hidden' grade='gform_hidden' name='gform_unique_id' value='' /> <input type='subconscious' class='gform_hidden' name='state_9' value='WyJbXSIsIjVkYTAyNjYxOTg4ZDNhZGQwOTU0Yzc4NDcyNDk5YmM4Il0=' /> <input blazon='hidden' class='gform_hidden' proper noun='gform_target_page_number_9' id='gform_target_page_number_9' value='0' /> <input blazon='hidden' class='gform_hidden' proper name='gform_source_page_number_9' id='gform_source_page_number_9' value='1' /> <input type='subconscious' name='gform_field_values' value='popup_name=Food+Additives' /> </div> <p manner="display: none !of import;"><label>Δ<textarea proper noun="ak_hp_textarea" cols="45" rows="viii" maxlength="100"></textarea></characterization><input blazon="hidden" id="ak_js_7" name="ak_js" value="35"/><script>document.getElementById( "ak_js_7" ).setAttribute( "value", ( new Date() ).getTime() );</script></p></form> </div>
[gravityform id="ix" championship="false" description="false" field_values='popup_name=Diet-Eye Myth']
<div class='gf_browser_chrome gform_wrapper qc_box_container_wrapper gform_legacy_markup_wrapper' id='gform_wrapper_9' ><class method='postal service' enctype='multipart/form-information' id='gform_9' class='qc_box_container gform_legacy_markup' activity='/three-reasons-why-your-thyroid-medication-isnt-working/' novalidate> <div class='gform_body gform-body'><ul id='gform_fields_9' class='gform_fields top_label form_sublabel_below description_below'><li id="field_9_1" grade="gfield field gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible" ><label grade='gfield_label' for='input_9_1' >Electronic mail<span class="gfield_required"><span class="gfield_required gfield_required_asterisk">*</span></span></label><div class='ginput_container ginput_container_email'> <input name='input_1' id='input_9_1' type='email' value='' class='large' placeholder='Your Email' aria-required="true" aria-invalid="false" /> </div></li><li id="field_9_2" class="gfield health-concern field field_sublabel_below field_description_below gfield_visibility_visible" ><label course='gfield_label' for='input_9_2' >I want to ameliorate my...</characterization><div grade='ginput_container ginput_container_select'><select proper name='input_2' id='input_9_2' class='large gfield_select' aria-invalid="false" ><option value='' selected='selected' class='gf_placeholder'>I want to amend my...</choice><selection value='Weight' >Weight</option><option value='Energy' >Free energy</choice><selection value='Digestion' >Digestion</choice><option value='Brain' >Encephalon</option><pick value='Overall Health' >Overall Health</option><choice value='All of the Higher up' >All of the Above</choice></select></div></li><li id="field_9_4" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input name='input_4' id='input_9_4' blazon='subconscious' class='gform_hidden' aria-invalid="false" value='791' /></div></li><li id="field_9_5" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div course='ginput_container ginput_container_text'><input name='input_5' id='input_9_5' type='hidden' course='gform_hidden' aria-invalid="false" value='Diet-Heart Myth' /></div></li></ul></div> <div form='gform_footer top_label'> <input type='submit' id='gform_submit_button_9' class='gform_button button' value='Download eBook' onclick='if(window["gf_submitting_9"]){return false;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=truthful;} ' onkeypress='if( outcome.keyCode == 13 ){ if(window["gf_submitting_9"]){return imitation;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} jQuery("#gform_9").trigger("submit",[true]); }' /> <input type='hidden' class='gform_hidden' proper name='is_submit_9' value='ane' /> <input blazon='hidden' form='gform_hidden' proper name='gform_submit' value='9' /> <input type='subconscious' class='gform_hidden' proper name='gform_unique_id' value='' /> <input type='hidden' class='gform_hidden' name='state_9' value='WyJbXSIsIjVkYTAyNjYxOTg4ZDNhZGQwOTU0Yzc4NDcyNDk5YmM4Il0=' /> <input blazon='subconscious' class='gform_hidden' proper name='gform_target_page_number_9' id='gform_target_page_number_9' value='0' /> <input type='subconscious' form='gform_hidden' name='gform_source_page_number_9' id='gform_source_page_number_9' value='1' /> <input blazon='hidden' name='gform_field_values' value='popup_name=Diet-Heart+Myth' /> </div> <p style="brandish: none !important;"><characterization>Δ<textarea name="ak_hp_textarea" cols="45" rows="8" maxlength="100"></textarea></label><input blazon="subconscious" id="ak_js_8" proper name="ak_js" value="8"/><script>document.getElementById( "ak_js_8" ).setAttribute( "value", ( new Date() ).getTime() );</script></p></form> </div>
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<div class='gf_browser_chrome gform_wrapper qc_box_container_wrapper gform_legacy_markup_wrapper' id='gform_wrapper_9' ><form method='post' enctype='multipart/form-data' id='gform_9' grade='qc_box_container gform_legacy_markup' action='/three-reasons-why-your-thyroid-medication-isnt-working/' novalidate> <div class='gform_body gform-torso'><ul id='gform_fields_9' class='gform_fields top_label form_sublabel_below description_below'><li id="field_9_1" class="gfield field gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible" ><label class='gfield_label' for='input_9_1' >Email<span grade="gfield_required"><span class="gfield_required gfield_required_asterisk">*</span></bridge></characterization><div grade='ginput_container ginput_container_email'> <input proper noun='input_1' id='input_9_1' blazon='email' value='' class='large' placeholder='Your Email' aria-required="true" aria-invalid="fake" /> </div></li><li id="field_9_2" grade="gfield health-business organisation field field_sublabel_below field_description_below gfield_visibility_visible" ><label course='gfield_label' for='input_9_2' >I desire to ameliorate my...</characterization><div form='ginput_container ginput_container_select'><select proper noun='input_2' id='input_9_2' class='large gfield_select' aria-invalid="simulated" ><option value='' selected='selected' class='gf_placeholder'>I want to improve my...</selection><option value='Weight' >Weight</option><choice value='Free energy' >Energy</option><option value='Digestion' >Digestion</pick><option value='Brain' >Encephalon</option><option value='Overall Wellness' >Overall Health</option><option value='All of the Higher up' >All of the Above</selection></select></div></li><li id="field_9_4" class="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div form='ginput_container ginput_container_text'><input proper name='input_4' id='input_9_4' blazon='hidden' class='gform_hidden' aria-invalid="false" value='791' /></div></li><li id="field_9_5" grade="gfield gform_hidden field_sublabel_below field_description_below gfield_visibility_visible" ><div class='ginput_container ginput_container_text'><input name='input_5' id='input_9_5' type='subconscious' course='gform_hidden' aria-invalid="imitation" value='B12' /></div></li></ul></div> <div class='gform_footer top_label'> <input type='submit' id='gform_submit_button_9' class='gform_button push button' value='Download eBook' onclick='if(window["gf_submitting_9"]){render imitation;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} ' onkeypress='if( event.keyCode == 13 ){ if(window["gf_submitting_9"]){return false;} if( !jQuery("#gform_9")[0].checkValidity || jQuery("#gform_9")[0].checkValidity()){window["gf_submitting_9"]=true;} jQuery("#gform_9").trigger("submit",[truthful]); }' /> <input type='subconscious' class='gform_hidden' proper name='is_submit_9' value='one' /> <input type='hidden' class='gform_hidden' proper noun='gform_submit' value='9' /> <input blazon='hidden' class='gform_hidden' name='gform_unique_id' value='' /> <input type='subconscious' grade='gform_hidden' name='state_9' value='WyJbXSIsIjVkYTAyNjYxOTg4ZDNhZGQwOTU0Yzc4NDcyNDk5YmM4Il0=' /> <input type='subconscious' course='gform_hidden' name='gform_target_page_number_9' id='gform_target_page_number_9' value='0' /> <input type='hidden' grade='gform_hidden' name='gform_source_page_number_9' id='gform_source_page_number_9' value='1' /> <input type='hidden' name='gform_field_values' value='popup_name=B12' /> </div> <p style="display: none !important;"><label>Δ<textarea proper noun="ak_hp_textarea" cols="45" rows="8" maxlength="100"></textarea></label><input type="hidden" id="ak_js_9" name="ak_js" value="1"/><script>document.getElementById( "ak_js_9" ).setAttribute( "value", ( new Date() ).getTime() );</script></p></form> </div>
Source: https://chriskresser.com/three-reasons-why-your-thyroid-medication-isnt-working/
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